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The Neurobagel Query Tool

Neurobagel's query tool is a web interface for searching across a Neurobagel graph based on various subject clinical-demographic and imaging parameters.

The query tool is a React application, developed in TypeScript using a variety of tools including Vite, Cypress, and MUI.

Quickstart

The query tool is hosted at https://query.neurobagel.org/ and interfaces with Neurobagel federation API.

Local Installation

To run the query tool locally, you have two options:

  1. Use our docker image
  2. Do a manual install from the cloned git repo.

but before proceeding with either you need to set the environment variables.

Mandatory configuration

Environment variable Type Required Default value if not set Example
NB_API_QUERY_URL string Yes - https://federate.neurobagel.org/
NB_QUERY_APP_BASE_PATH string No / /query/
NB_ENABLE_AUTH boolean No false false
NB_QUERY_CLIENT_ID string Yes (if NB_ENABLE_AUTH is set to true) - 46923719231972-dhsahgasl3123.apps.googleusercontent.com

NB_API_QUERY_URL

You'll need to set the NB_API_QUERY_URL environment variable required to run the query tool. NB_API_QUERY_URL is the Neurobagel API URL that the query tool uses to send requests to for results.

NB_QUERY_APP_BASE_PATH

If you are using a custom configuration where the query tool is accessible via a path other than the root (/), you need to set the NB_QUERY_APP_BASE_PATH to your custom path. This ensures that the query tool is correctly rendered and accessible at the specified URL

NB_ENABLE_AUTH

If the API you'd like to send queries to requires authentication, you need to set NB_ENABLE_AUTH to true as it is false by default. This will enable authentication flow of the app.

NB_QUERY_CLIENT_ID

If the NB_ENABLE_AUTH is set to true (it is false by default), you need to provide a valid client ID for the authentication. At the moment, query tool uses Google for authentication, so you need to obtain a client ID from Google developer console. See documentation for more information.

Set the environment variables

To set environment variables, create a .env file in the root directory and add the environment variables there. If you're running a neurobagel node-API locally on your machine (following the instructions here), your .env file would look something like this:

NB_API_QUERY_URL=http://localhost:8000/

if you're using the remote api, your .env file would look something like this:

NB_API_QUERY_URL=https://federate.neurobagel.org/

if you're using a remote api with authentication, your .env file would look something like this:

NB_API_QUERY_URL=https://federate.neurobagel.org/
NB_ENABLE_AUTH=true
NB_QUERY_CLIENT_ID=46923719231972-dhsahgasl3123.apps.googleusercontent.com

⚠ The protocol matters here. If you wish to use the Neurobagel remote API, ensure your NB_API_QUERY_URL uses https instead of http.

Docker installation

To obtain the query tool docker image, simply run the following command in your terminal:

docker pull neurobagel/query_tool:latest

This Docker image includes the latest release of the query tool and a minimal http server to serve the static tool.

To launch the query tool Docker container and pass in the .env file you have created, simply run

docker run -p 5173:5173 --env-file=.env neurobagel/query_tool:latest

Then you can access the query tool at http://localhost:5173

Note: the query tool is listening on port 5173 inside the docker container, replace port 5173 by the port you would like to expose to the host. For example if you'd like to run the tool on port 8000 of your machine you can run the following command:

docker run -p 8000:5173 --env-file=.env neurobagel/query_tool:latest

Manual installation

To install the query tool directly, you'll need node package manager (npm) and Node.js. You can find the instructions on installing npm and node in the official documentation.

Once you have npm and node installed, you'll need to install the dependencies outlined in the package.json file. You can do so by running the following command:

npm install

To launch the tool in developer mode run the following command:

npm run dev

You can also build and then run the tool from (production) build of the application by running the following command:

npm run build && npm run preview

You can verify the tool is running by watching for the` info messages from Vite regarding environment, rendering, and what port the tool is running on in your terminal.

Developer setup

Having installed the dependencies, run the following command to enable husky pre-commit and post-merge hooks:

npx husky install
Docker compose testing environment for development

Since the query tool relies on other neurobagel tools to function, their presence is often required during development. To facilitate this, a docker compose containing a complete testing environment has been created. To use it follow the steps below:

  1. Install recipes and neurobagel_examples submodules:
git submodule init
git submodule update
  1. Pull the latest images and bring up the stack using the test profile:
docker compose --profile test pull && docker compose --profile test up -d

NOTE: Make sure your .env file in the root directory doesn't contain any of the environment variables used in the docker compose file as it will conflict with the configuration, since docker compose will try to use .env by default.

Usage

To define a cohort, set your inclusion criteria using the following:

  • Age: Minimum and/or maximum age (in years) of participant that should be included in the results.
  • Sex: Sex of participant that should be included in the results.
  • Diagnosis: Diagnosis of participant that should be included in the results
  • Healthy control: Whether healthy participants should be included in the results. Once healthy control checkbox is selected, diagnosis field will be disabled since a participant cannot be both a healthy control and have a diagnosis.
  • Minimum number of sessions: Minimum number of imaging sessions that participant should have to be included in the results.
  • Assessment tool: Non-imaging assessment completed by participant that should be included in the results.
  • Modality: Imaging modality of participant scans that should be included in the results.

Once you've defined your criteria, submit them as a query and the query tool will display the results.\ The query tool offers two different TSV files for results:

  • Dataset-level results TSV contains: dataset id, dataset name, dataset portal uri, number of matching subjects, and available imaging modalities
  • Participant-level results TSV contains: dataset id, subject id, age, sex, diagnosis, assessment, session id, session file path, number of sessions, and imaging modality

The output files can be joined using DatasetID as key.

Downloading query results

For a given query, the query tool offers two kinds of TSV files for results that users can download. At least one dataset matching the query must be selected in the interface in order to download the query results.

Dataset-level results

The dataset-level results TSV describes the datasets that contain subjects matching the user's query. This TSV contains the following columns:

  • DatasetID: unique identifier (UUID) for dataset in the graph. Note that this ID is not guaranteed to be persistent across versions of a graph/across graphs, but will always be identical across a pair of query tool result files. This column can be used as the key to join the dataset-level and participant-level results TSVs for a given query result, if needed.
  • DatasetName: human readable name of the dataset
  • PortalURI: URL to a website or page about the dataset, if available
  • NumMatchingSubjects: (aggregate variable) number of subjects matching the query within the dataset
  • AvailableImageModalites: (aggregate variable) list of unique imaging modalities available for the dataset

Example:

DatasetID DatasetName PortalURI NumMatchingSubjects AvailableImageModalities AvailablePipelines
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 BIDS synthetic https://github.com/bids-standard/bids-examples 5 http://purl.org/nidash/nidm#FlowWeighted, http://purl.org/nidash/nidm#T1Weighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/fmriprep 23.1.3, https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2

Participant-level results

The participant-level results TSV contains the available harmonized participant attributes for subject sessions matching the query in each (selected) matching dataset. Each row in the TSV corresponds to a single matching subject session.

This TSV contains the following columns:

  • DatasetID: unique identifier (UUID) for dataset in the graph. Note that this ID is not guaranteed to be persistent across versions of a graph/across graphs, but will always be identical across a pair of query tool result files. This column can be used as the key to join the dataset-level and participant-level results TSVs for a given query result, if needed.
  • SubjectID: subject label
  • SessionID: the label of the session
  • SessionType: either ImagingSession or PhenotypicSession
  • Age: subject age, if available
  • Sex: subject sex, if available
  • Diagnosis: list of diagnoses of subject, if available
  • Assessment : list of assessments completed by subject, if available
  • SessionFilePath: the path of the session directory (for imaging sessions) either relative to the dataset root (for datasets available through DataLad) or relative to the root of the filesystem where the dataset is stored
  • NumPhenotypicSessions: (aggregate variable) total number of phenotypic sessions that match the query for a subject
  • NumImagingSessions: (aggregate variable) total number of imaging sessions that match the query for a subject This number will be the same across rows corresponding to the same subject.
  • Modality: imaging modalities acquired in the session, if available

Example:

DatasetID SubjectID SessionID SessionType Age Sex Diagnosis Assessment SessionFilePath NumPhenotypicSessions NumImagingSessions Modality CompletedPipelines
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-01 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-01/ses-01 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/fmriprep 23.1.3, https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-01 http://neurobagel.org/vocab/PhenotypicSession 34.1 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-01 http://neurobagel.org/vocab/Session 34.1 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-01/ses-01 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/fmriprep 23.1.3, https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-02 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-01/ses-02 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-02 http://neurobagel.org/vocab/PhenotypicSession 35.3 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-01 ses-02 http://neurobagel.org/vocab/Session 35.3 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-01/ses-02 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-01 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-02/ses-01 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/fmriprep 23.1.3, https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-01 http://neurobagel.org/vocab/PhenotypicSession nan http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008 https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-01 http://neurobagel.org/vocab/Session nan http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008, https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-02/ses-01 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/fmriprep 23.1.3, https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-02 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-02/ses-02 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-02 http://neurobagel.org/vocab/PhenotypicSession 39 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008 https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-02 ses-02 http://neurobagel.org/vocab/Session 39 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008, https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-02/ses-02 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted https://github.com/nipoppy/pipeline-catalog/tree/main/processing/freesurfer 7.3.2
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-01 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-03/ses-01 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-01 http://neurobagel.org/vocab/PhenotypicSession 22.1 nan nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-01 http://neurobagel.org/vocab/Session 22.1 nan nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-03/ses-01 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-02 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-03/ses-02 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-02 http://neurobagel.org/vocab/PhenotypicSession 23.2 nan http://purl.bioontology.org/ontology/SNOMEDCT/406506008 https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-03 ses-02 http://neurobagel.org/vocab/Session 23.2 nan http://purl.bioontology.org/ontology/SNOMEDCT/406506008, https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-03/ses-02 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-01 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-04/ses-01 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-01 http://neurobagel.org/vocab/PhenotypicSession 21.1 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-01 http://neurobagel.org/vocab/Session 21.1 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-04/ses-01 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-02 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-04/ses-02 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-02 http://neurobagel.org/vocab/PhenotypicSession 22.3 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-04 ses-02 http://neurobagel.org/vocab/Session 22.3 http://purl.bioontology.org/ontology/SNOMEDCT/248152002 nan https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-04/ses-02 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-01 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-05/ses-01 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-01 http://neurobagel.org/vocab/PhenotypicSession 42.5 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008 https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-01 http://neurobagel.org/vocab/Session 42.5 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008, https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-05/ses-01 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-02 http://neurobagel.org/vocab/ImagingSession nan nan nan nan /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-05/ses-02 2 2 http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-02 http://neurobagel.org/vocab/PhenotypicSession 43.2 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008 https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece nan 2 2 nan nan
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 sub-05 ses-02 http://neurobagel.org/vocab/Session 43.2 http://purl.bioontology.org/ontology/SNOMEDCT/248153007 http://purl.bioontology.org/ontology/SNOMEDCT/406506008, https://www.cognitiveatlas.org/task/id/trm_57964b8a66aed, https://www.cognitiveatlas.org/task/id/tsk_4a57abb949ece, /data/neurobagel/bagel-cli/bids-examples/synthetic/sub-05/ses-02 2 2 , http://purl.org/nidash/nidm#T1Weighted, http://purl.org/nidash/nidm#FlowWeighted nan

protected participant-level results in aggregate mode

If the values for all columns except for DatasetID and SessionPath in the participant-level results tsv are set to protected, this indicates the graph being queried has been configured (via its corresponding Neurobagel node API) to return only aggregate information about matches (due to data privacy reasons). This configuration can be modified by setting the NB_RETURN_AGG environment variable to false (the value is by default true). See related section of the documentation here.

Example:

DatasetID SubjectID SessionID SessionType Age Sex Diagnosis Assessment SessionFilePath NumPhenotypicSessions NumImagingSessions Modality CompletedPipelines
http://neurobagel.org/vocab/838f54dd-bc3c-4469-8795-b5e280ae0f82 protected protected protected protected protected protected protected protected protected protected protected protected

Testing

The query tool utilizes Cypress framework for testing.

To run the tests execute the following command:

npx cypress open

License

The query tool is released under the terms of the MIT License